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5-chloro-n-{(3s)-1-[(2s)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1h-indole-2-sulfonamide

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule arylsulfonamide, specifically an indole sulfonamide derivative. It is structurally characterized by the presence of a morpholine ring, a pyrrolidine moiety, and an indole core substituted with a sulfonamide group and chlorine at the fifth position. The compound has been identified as "Arylsulfonamide 3b" in chemical databases and is reported to act as an inhibitor of coagulation factor X (also known as Factor Xa), which plays a central role in the blood coagulation cascade. As such, it may have potential applications as an anticoagulant or antithrombotic agent; however, there are no records of clinical development or approval for therapeutic use[6]. No information on its developer or manufacturer was found.

Other names
5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide5-Chlor-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo–3-pyrrolidinyl}-1H-indol–2-sulfonamid5-chloro-n-{(3s)-1-[ (2s) - 1 - (4-morpholinyl) - 1 - oxo – 2 – propanyl ] – 2 – oxo – 3 – pyrrolidinyl }– indole– sulfonamide
02

Targets

F10 (Factor Xa)

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